We are pleased to announce that starting today, your applications running on Amazon EC2 instances can be directly fronted by AWS Global Accelerator. Before, you needed to use an Application Load Balancer, Network Load Balancer, or Elastic IP address to front an EC2 instance with Global Accelerator. Now, you can use Global Accelerator directly as your single internet-facing access point for your EC2 instances, improving availability and performance of applications with local or global users.

from Recent Announcements https://aws.amazon.com/about-aws/whats-new/2019/10/aws-global-accelerator-supports-ec2-instance-endpoints/