AWS Direct Connect is now live at CDLAN srl Via Caldera 21, Milano. This is the first AWS Direct Connect location in Italy. Customers in Milan can now locally establish a dedicated network connection from their premises to AWS. This location can be found in the Management Console. With global access for AWS Direct Connect, you can reach AWS resources in any global AWS region from any of the above locations using global public VIFs and Direct Connect Gateway. When connecting to any AWS region, your data will not hairpin via the home region if it is not in the shortest path to your desired AWS region. 

from Recent Announcements https://aws.amazon.com/about-aws/whats-new/2019/06/aws_direct_connect_locations_in_italy/